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外伤性癫痫的手术治疗(附25例分析) 被引量:16

Surgery for the Treatment of Traumatic Epilepsy
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摘要 目的探讨外伤性癫痫手术治疗的效果。方法外伤性癫痫25例,首次癫痫发作在颅脑损伤后3 ̄15年。术前患者均行了EEG检查和CT或MRI检查,另外7例患者还行发作间期SPECT检查。在ECoG监测下对患者进行手术治疗。结果术后半年以上随访显示手术总有效率为84.0%(21/25),优良率为80.0%(20/25)。其中16例行皮质切除术患者中14例有效;4例行前颞叶切除术的患者均有效;4例行单纯胼胝体切开术的患者例有效2,2例效果较差;1例行胼胝体切开多处软脑膜下横纤维切断+(MST)的患者有效。结论外伤性癫痫是顽固性癫痫中手术疗效较好的一种类型。如果药物治疗的效果不佳,且术前致痫灶定位准确,就可以考虑手术治疗。 Objective To explore the effect of surgery on traumatic epilepsy. Method The first seizure occurred 3~15 years after craniocerebral injury in 25 patients with epilepsy. EEG and CT or MRI were preoperatively performed in all the patients. SPECT exa-mination was done in 7 patients. All the patients underwent the operations under ECoG. Results The follow-up for more than half a year showed that the total effective rate of epilepsy surgery was 84.0% (21/25) and excellent rate was 80% (20/25). The effective result was achieved in 14 of 16 patients undergoing cortical resection. The anterior temporal lobectomy was effective in all the 4 patients with epilepsy. Of 4 patients undergoing corpus collotomy, 2 received effective outcome and 2 bad. One patient receiving mutiple subpial transection and corpus collotomy was recovered from his illness. Conclusion The traumatic epilepsy is a kind of refractory epilepsy with better surgical effect. The epileptic lesion should be surgically resected when it can not be controlled by anti-epileptic drugs.
出处 《中国临床神经外科杂志》 2005年第1期5-7,共3页 Chinese Journal of Clinical Neurosurgery
关键词 外伤性癫痫 手术 疗效 Traumatic epilepsy Surgery Curative effect
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参考文献5

  • 1尹海斌,谭春祥,张光祥,曾文胜,李峰.外伤性癫痫的手术治疗(附32例临床总结)[J].医师进修杂志,2002,25(9):40-40. 被引量:6
  • 2李龄,沈成鑫.镍伤后癫痫的手术治疗[J].中华外科杂志,1991,29(4):242-243. 被引量:2
  • 3Temkin NR. Risk factors for posttraumatic seizures in adults[J]. Epilepsia, 2003, 44 (Suppl 10): 18-20.
  • 4Ognezlev KIa, Shaginian GG, Druzhinin VS, et al. The role of computed tomography in the diagnosis of brain involvement in patients with post-traumatic epilepsy [J]. Vestn Rentgenol Radiol, 1992, 5: 39-42.
  • 5Englander J, Bushnik T, Duong "IT, et al . Analyzing risk factors for late posttraumatic seizures: a prospective, multicenter investigation [J]. Arch Phys Med Rehabil, 2003, 84(3): 365-373.

二级参考文献3

  • 1李龄,同济医科大学学报,1989年,18卷,112页
  • 2谭启富,中国神经精神疾病杂志,1984年,10卷,22页
  • 3赵雅度,中华神经精神科杂志,1965年,9卷,325页

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