摘要
缝隙连接(gap junction,GJ)是含有多种细胞间通道的特殊膜结构,由连接蛋白(connexin,Cx)所构成,Cx40含量和分布的改变,可导致心房肌细胞电耦联传导速度改变,增加折返性心律失常,从而产生心房颤动(atrial fibrillation)。本文对连接蛋白与心房颤动之间关系的研究进展作一综述。
Gap junction, a special membrane structure communicating many kinds of cells, is composed of connexin.Changes of connexin levels and distribution can lead to changes of conduction velocity of electric couple and increase of reentrant arrhythmia, finally to atrial fibrillation. This article elucidates the relationship between cardiac gap junction protein connexin and atrial fibrillation.
出处
《第二军医大学学报》
CAS
CSCD
北大核心
2005年第2期208-210,共3页
Academic Journal of Second Military Medical University
基金
国家自然科学基金(30070749)
关键词
缝隙连接
连接蛋白
心房颤动
gap junction
connexin
atrial fibrillation
