摘要
目的:比较灯盏细辛注射液和灯盏花素的成分异同。方法:高效液相色谱 二极管阵列检测法(HPLC DAD):Hyper silODS2(250×4.6mm,5μm)色谱柱,乙腈 水 磷酸(18∶82∶0.2)为流动相,流速0.8ml/min,检测波长286nm,柱温40°C。 结果:灯盏细辛注射液色谱图中有10个峰的紫外光谱与咖啡酸的吸收带和谱线轮廓相似、野黄芩苷的峰极低;灯盏花素 片色谱图的主要峰为野黄芩苷峰。结论:临床用途相同的灯盏细辛注射液与灯盏花素片在主要化学成分类型上截然不 同。
AIM: To compare the chemical constituents of Injectio erigerontis and breviscapine. METHODS: High performance liquid chromatography and diotron array detection (HPLC-DAD) was adopled with Hypersil ODS2 Column (250 mm×4.6 mm,5 μm), and mobile phase was acetonitrile-H 2O-H 3PO 4(18∶82∶0.2),detection wavelength was at 286 nm, temperature was at 40 °C. RESULTS: Weak peaks of Seutellarin and caffeic acid were resembling between injetio erigerontis and breviscapine in UV spectra. but Injectio eriperontis possibly contained 10 catteic acid derivatives. CONCLUSION: Injectio erigerontis and breviscapine are completely different in chemical constituents,though their clinic application and curative effect are equal.
出处
《中成药》
CAS
CSCD
北大核心
2005年第2期202-204,共3页
Chinese Traditional Patent Medicine
