摘要
目的 比较米非司酮合并米索前列醇和负压吸宫术 2种终止早孕方法的临床效果及对流产后月经的影响。方法 将 4 0 0例停经 4 9d内的早孕妇女根据自愿原则分为 2组 ,药流组 2 0 0例 ,采用常规药流法 ;人流组 2 0 0例 ,采用人工负压宫腔内吸引法 ,并对这 2种方法的流产效果、副反应、流产后阴道出血情况、对月经的影响及可接受性等方面进行比较。结果 药流组中年龄 <2 5岁 ,初孕妇女比例明显高于人流组 (P <0 0 1) ;人流组中年龄 >30岁 ,经产妇女的比例高于药流组 (P <0 0 1) ;人流组的流产效果、阴道出血持续时间、出血量等均较药流组好 (P <0 0 1) ;两组对流产后 3个月月经的影响基本相似 (P >0 0 5 ) ;2组很满意和满意程度调查结果基本相似 (P >0 0 5 ) ,但孕妇选择原因上有所不同。结论 药物流产和负压吸宫术终止早孕各具优缺点 ,均是安全、有效、副作用小的好方法 。
Objective To prospectively compare the clinical efficacy of medical abortion and induced abortion in the terminaiton of early pregnancy and the influence on menstruation. Methods 400 pregnant women less than 49 day amenorrhea were allocated into two groups to their request: medical abortion group ( n =200), taking mifepristone 25 mg every 12 h for 2 days and then misopostol 600 μg at 8:00 on the third day; and induced abortion group ( n =200), subject to the routine intrauterine operation by vacuum aspirator. Outcome measures included the efficacy, side effects, vaginal bleeding, influence on menstruation and acceptability of the two abortion procedures. Results Nullipara less than 25 years old prefered to medical abortion rather than induced abortion ( P <0 01); However, those who were over 30 years and parous prefered to induced abortion ( P <0 01); As for clinical efficacy and vaginal bleeding volume and time were concerned, medical abortion group was better than induced abortion group ( P <0 01); There were no significant differences between the two groups in the following 3 menstrual cycles; The results of preference survey were similar ( P >0 05). Conclusion Both methods were safe, effective and had slight side effects, which could never be substituted by each other.
出处
《华中科技大学学报（医学版）》
CAS
CSCD
北大核心
2003年第4期416-418,共3页
Acta Medicinae Universitatis Scientiae et Technologiae Huazhong
