摘要
本文应用免疫放射分析法对46例大肠癌患者进行血清糖类抗原CA-50测定,阳性率为 63.04％,均值为 29.57±77.60μ/ml。发现浸润型癌、粘液癌、高分化腺癌 CA—50值明显升高,并与肿瘤大小、侵犯深度、转移情况等呈正相关。提示CA-50值越高,临床病期越晚,手术切除肿瘤的可能性越小,预后亦差。术后定期复查CA-50,如持续不降或下降后又升高,说明肿瘤有复发或转移之可能。
Serum CA-50 value was determined by immunoradiometric assay (IRMA) in 46 petients with col- orectal cancer. The positive rate was 63. 04％ with a mean value 29. 57±77. 60μ/ml. Markedly high value of CA-50 was found in infiltrative carcinoma, colloid and highly differentiated cancer. The value of CA-50 was positively correlated with the size of the tumor,depth of invasion and metastasis. The higher was the value of the CA-50, the more advanced stage of the disease was and the less probability of surgical removal of the cancer and the poorer prognosis would be.The persistently high value of CA-50 or its decrement followed by an increase after resection suggested a relapse or metastasis of the cancer.
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
1993年第11期865-867,共3页
Chinese Journal of Clinical Oncology
关键词
糖类
抗原
CA-50
癌
大肠肿瘤
Colorectal cancer
Glycoprotein antigen
CA-50
Tumor marker
