摘要
Wistar 大鼠一次经口灌入氚化赖氨酸,在灌入氚后的不同时间测定分析了主要组织器官中总氚(湿组织中的氚)和结合氚(干组织中的氚)的活度,并根据组织中的氚活度估算了氚至组织的剂量率。实验结果表明,氚在组织中的活度随氚灌入后时间的延长按指数下降规律逐步降低,其分布不很均匀。肾和肝中的氚活度高于血和睾丸,而睾丸最低。氚灌入后第15天时在组织中的滞留活度约占第一天的 9 ％左右。组织剂量率的排列范围为肝10×10^(-8)～2.0×10^(-8);肾11×10^(-8)～1.9×10^(-8);血6.0×10^(-8)～1.6×10^(-8);睾丸3.7×10^(-6)～1.2×10^(-8)。从剂量率的估算结果看,随氚摄入后时间增加剂量率逐渐降低,第10天时最低。
The metabolism of tritium in tissues of Wistar rats was studies by single oral intubationof tritium-labelled lysine. Experimental results showed that the concentrations of tritium inwet tissues (total tritium) and dry tissues (organically bound tritium) dropped gradually withtime. On the 15th day after oral intubation, the retention of tritium in the rats tissues was aq-out 9 percent of that on 1st day. Higher concentration of tritium and larger radiation doseswere found in kidney and livei, and the lowest values were observed in testis.
出处
《卫生毒理学杂志》
CSCD
1993年第3期149-150,F003,共3页
Journal of Health Toxicology
