摘要
该院在23年中共收住官颈癌16210例,经放疗后继发宫体恶性肿瘤17例(占0.11％),其中资料完整的有11例(宫体腺癌5例,宫体中胚叶混合瘤6例)。作者认为放疗是发生此类肿瘤的重要因素。经宫颈癌放疗后长期存活的患者,阴道排液多和出血。尤其对伴宫体增大积液者,应考虑本病的可能。内膜活检是主要的诊断手段。治疗方法主要是手术。1例中胚叶混合瘤术后配合化疗,存活3年;另1例宫体腺癌术后已3年余至今健在.对该肿瘤应及早诊断,并采用手术、化疗、免疫治疗等综合措施,可望提高疗效。
Eleven cases with malignancy of uterine corpus occurred among 16,210 cases with cervical cancer in 10-23 years after radiotherapy. Six cases were malignant mixed mesodermal tumour and 5 endometrial carcinoma. Six of the 11 patients were diagnosed by endometrial biopsy before treatment and the other 5 by postoperative pathology. Seven cases complained of vaginal bleeding and 6 of vaginal discharge. The enlarged uterine corpus was found in all patients and underwent surgery. Ten patients died of the disease within 3 years and only one survived for 3 years. Our data and other authors' experience showed that the prognosis of the malignant uterine tumour after radiotherapy for cervical cancer was very poor and early diagnosis was very important. We believe that the combination therapy of surgery, chemotherapy and immunotherapy may improve the survival rate.
出处
《上海医学》
CAS
CSCD
北大核心
1989年第4期205-207,共3页
Shanghai Medical Journal
