摘要
迄今为止的研究证明,血液流变因素贯穿于循环系统的所有部分和方面。许多流变参数的改变反映了体内特定的病理生理过程或状态,因而可作为临床诊断和治疗的参考指标。 为了将血液流变学的理论、方法和手段应用于心血管外科,作者连续测定了153例(957份血样)患者在围手术期的六个方面84个流变指标及其变化。发现多参数的流变测定确可加深对心外科患者的许多病理生理过程或状态的认识,因而可为临床诊疗提供参考。为此,特将资料分析整理,陆续报道,以供同行参考。 流变测定的科学化和标准化问题已成为影响学科发展的一个重要因素。作者为了较为科学地对心外科类血液流变问题进行探讨,特对实验设备的配套、标定、实验设计和条件控制,以及测试标准化方面进行了研究,并和国际标准化委员会所发ICSH文件中有关部分进行了对照;继后,对178例正常人进行了测定。
Rheological methOds used in clinical studies have suffered from lack of standardization and poor comparirsion between laboratories. It is now a serious problem to the development of hemorheology, especialy to clinical application.In order to study the hemotheological phenomena in cardiovascular surgery strictly, the author, at first, concentrated on forming a complete set of hemorheological instrument and designing some standardized hemorheological tests. The standards and control conditions which have been used inour laboratory are roughly identical with ICSH document.Based on the mentioned work, 957 blood samples from 153 cases of cardiac surgery were measured and compared with 178 cases of the normal group; It is shown that the changing parameters of patients' hemorheological properties during the perioperative period can reflect some important pathological courses or states and bring out many aspects significant in clinical practice. These results will be reported in succession.
出处
《生物医学工程学杂志》
EI
CAS
CSCD
北大核心
1989年第2期85-91,共7页
Journal of Biomedical Engineering
