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曲马多PVC膜选择性电极的研制 被引量:1

DEVELOPMENT OF SELECTIVE PVC MEMBRANE ELECTRODE FROM TRAMADOL
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摘要 介绍了一种曲马多PVC膜电极。该电极以曲马多——四苯硼缔合物为电活性物质,线性范围为4.0*10 ̄(-5)—4.0*10 ̄(-2)mol/L,检测下限为1.4*10 ̄(-5)mol/L,斜率为59.8mV/pc。电极在pH=3.0-7.0之间对曲马多的回收率为96.7%,电极被用于曲马多片剂和针剂中曲马多的含量测定,取得了较为满意的结果。 A PVC membrane electrode of tramadol was prepared and tested.The electroactive materi-al of the electrode was tramadol-tetraphenylborate complexes.The linear range of the elec-trode ws from 4.0 * 10^(-5)to 4.0 *10^(-2)mol / L. the detective limit and the slope were1.4*10^(-5)mol/ L and 59.8mV/ pc respectively.Between pH=3.0 and pH=7.0,the recoveriesof tramadol are 96.7%. The electrode was used to measure the concentration of tramadol in tab-Iets and injection with sytisfactory results
出处 《河南科学》 1994年第2期119-122,共4页 Henan Science
关键词 曲马多 PVC膜 离子选择电极 止痛药 Tramadol PVC membrane Ion selective mambrane
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  • 1李丙寅,张治军,依慧,陈振乾.莨菪类药物电极的研究——Ⅰ、PVC膜阿托品电极的研制及应用[J]河南大学学报(自然科学版),1984(04).
  • 2Naoki Kamo,Makoto Muratsugu,Ruji Hongoh,Yonosuke Kobatake. Membrane potential of mitochondria measured with an electrode sensitive to tetraphenyl phosphonium and relationship between proton electrochemical potential and phosphorylation potential in steady state[J] 1979,The Journal of Membrane Biology(2):105~121

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