摘要
本文检测了３８例自身免疫病患者红细胞超氧化物歧化酶活性（Ｅｒｙ－ＳＯＤＡ），全血谷脱甘肽过氧化物醇（ＧＳＨ－Ｐｘ）活性及血浆丙二醛（ＭＤＡ）含量。结果表明；与正常对照组比较，自身免疫病组Ｅｒｙ－ＳＯＤＡ显著下降，ＧＳＨ－Ｐｘ活性和ＭＤＡ含量明显升高。血瘀证组与非血瘀证组比较，ＧＳＨ－Ｐｘ活性升高具有显著意义，（Ｐ＜０．０１），而Ｅｒｙ－ＳＯＤＡ降低和ＭＤＡ升高经统计学处理无显著意义（Ｐ＞０．０５）。提示自身免疫病的发生、发展与自由基损伤有密切关系，并且血瘀证患者自由基损伤程度更加严重。
Author determined malondialdehyde(MDA) contents in plasma,orythrocyte superoxide dismutase activities(Ery-SODA) and blood glutathione peroxidase(GSH-Px) activities for 38 cases of autoimmune disease(AID).The results showed thatEry-SODA in AID group and Blood Stasis Syndrome(BSS)group significantly decrease andGSH-Px activities and MDA Conents markedly increase compared with healthy controlgroup They also showed that GSH-Px activities markedly increase and the decrease ofEry-SODA and the increase of MDA contents in BSS group have no statistical significancecompared with Non-Blood Stasis Syndrome group.All above suggested that free radicals in-ury may participate in the occurrence of AID and BSS of AID.
出处
《湖南中医学院学报》
1994年第3期47-50,共4页
Journal of Hunan College of Traditional Chinese Medicine
关键词
自身免疫性疾
血瘀
病理学
自由基
Auttoimmune disease / pathology, free radicals, Superoxidedismutased / blood, gutathione peroxidases / blood,malondialehyde/blood,bloodstasis / pathology
