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肺内肿瘤病变的核仁组成区(NORs)研究及其对肿瘤良恶性鉴别的病理学意义 被引量:1

NUCLEOAR ORGANIZER REGIONS INVESTIGATION OF PULMONARY TUMORS AND ITS PATHOLOGIC SIGNIFICANCE
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摘要 本文报告了170例肺内各种肿瘤性病变的AgNORs检测结果。结论是:瘤样病变和良性瘤与各恶性瘤的组间差异非常显著(P<0.01).鳞癌和腺癌的高、中、低不同分化组之间无显著差异。肺内易于误诊为腺癌的腺样化生区,其AgNORs值与正常上皮相似,但有明显增生并有一定异型的上皮部分,其AgNORs值与恶性肿瘤相接近。作者认为:肺内瘤样及肿瘤病变的AgNORs测定对肿瘤病变的良恶性诊断有重要的辅助诊断作用。 ilver-binding Nucleolar Organizer Regions(AgNORs)were quantitavely countedin 170 cases of pulmonary tumors.The ultrastructure of NORs in 6 cases were obser-ved with electronic microscopy,It is considered that AgNORs counting might be a usefulindicator to differentiate between benign or tumor-like lesions with malignant tumors.AgNORs value of low-malignant tumors(such as carcinoid, mucoepithelial tumor,ade-nocystic carcinoma)might be between that in benign and malignant tumors,while thereWere no significant differences in groups of high-middle-low differentiation of squa-mous and adenocarcinoma in lung cancer,among high,middle and low malignantsquameus careinoma or adenocarcinoma of lung。
出处 《上海医学》 CSCD 北大核心 1994年第2期67-69,共3页 Shanghai Medical Journal
关键词 肺肿瘤 鉴别诊断 病理 Pulmonary tumors AgNORs
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  • 1丛文铭,中华病理学杂志,1991年,20卷,98页
  • 2詹--洲,第二军医大学学报,1990年,11卷,299页

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