摘要
目的 评价帕罗西汀佐治病毒性肝炎的临床疗效。方法 对新入院的病毒性肝炎病人随机分为帕罗西汀组及对照组,分别于入院时、治疗 2周末、4周末、6周末查HAMD、HAMA和肝功能,并分别进行比较。结果 帕罗西汀组患者 4周末的黄胆、胆汁酸及碱性磷酸酶水平分别为 15. 33±11. 53、10. 55±15. 72、294. 43±142. 05, 6周末的黄胆、胆汁酸、碱性磷酸酶水平分别为 10. 15±3. 74、8. 54±10. 11、214. 19±130. 12;对照组患者 4周末的黄胆、胆汁酸及碱性磷酸酶水平分别为 25. 55±28. 22、54. 68±72. 97、396. 39±240. 79, 6周末的黄胆、胆汁酸、碱性磷酸酶水平分别为 18. 46±8. 34、34. 98±60. 79、318. 29±220. 18。两组间比较差异有显著性。结论 帕罗西汀佐治病毒性肝炎不但能明显改善患者情绪,且十分有利于肝功能的恢复,值得临床推广使用。
ObjectiveTo evaluate the therapeutic effect of Paroxetine in treating viral hepatitis.MethodsEvery new-inpatients must examinate HAMD,HAMA and the levels of hepatitic function in 2-week later,4-week later,6-week later respectively .Results The level of jaundice,bile acid,akaline phosphatase are 15.33±11.53,10.55±15.72,294.43±142.05 in Paroxetine group after 4-week’s treatment,and the level of jaundice,bile acid,akaline phosphatase are 10.15±3.74,8.54±10.11,214.19±130.12 in Paroxetine group after 6-week’s treatment;The level of jaundice,bile acid,akaline phosphatase are 25.55±28.22,54.68±72.97,396.39±240.79 in controlled group 4-week’s later,and are 18.46±8.34,34.98±60.79,318.29±220.18 6-week’s later.There are significant difference between two groups.ConclusionThe hepatitic patients treated with Paroxetine can improve emotion and in favor of hepatitic function.So it can be used widely in clinical.
出处
《中国行为医学科学》
CSCD
2005年第3期234-235,共2页
Chinese Journal of Behavioral Medical Science
