摘要
测定了１７３例孕妇及８１例胎儿血清ＣＭＶ抗体。结果：１７３例孕妇血清中ＣＭＶ－ＩｇＧ阳性率为７０．５％（１２２／１７３），ＣＭＶ－ＩｇＭ阳性率为０．５８％（１／１７３），孕妇早、中、晚孕期ＣＭＶ感染率分别为５２％、７２．９％，７４．４％，妊娠次数≥４次的孕妇ＣＭＶ感染率较高。８１例脐血血清中ＣＭＶ－ＩｇＧ阳性率为５４．３％（４４／８１），ＣＭＶ－ＩｇＭ阳性率为６．２％（５／８１），５例先天性ＣＭＶ感染儿分别为４例胎儿畸形及１例产前咨询者，后者取脐血查到ＩｇＭ阳性后１个月，胎死宫内。提示脐血中一旦查到ＣＭＶ－ＩｇＭ阳性，胎儿有严重后果。因此，产前诊断胎儿ＣＭＶ感染，早期发现ＣＭＶ感染儿，是非常重要的。
To investigate cytomegalovirus(CMV)infection in pregnant women and fetuses, we examined the antibody of CMV in 173 pregnant women serum and 81 cord serum.The result revealed that the positive rate of CMV-IgG, CMV-IgM was 70.5% (122/173),0.58% (1/173)respectively. CMV infection rates in first, second and third trimesters were 52%, 72.9% and 74.4% respectively.The rate of CMV infection was higher when previous pregnancies were over4 times.The positive rate of CMV-IgG and CMV-IgM in 81 cord serum were 54.3% (44/81) and 6.2% (5/81).Thus,there were 5 fetuses suffering fromCMV infection. Among these fetuses,4 had obvious deformities and 1consulting case who resulted in intrauterine death one month later.The above result indicated that fetal damage might be very severe when CMV-IgM was positive in cord blood. Hence, prenatal diagnosis of fetal CMV infection is very important.
出处
《现代妇产科进展》
CSCD
1994年第1期19-22,共4页
Progress in Obstetrics and Gynecology
关键词
巨细胞病毒
胎儿
先天性感染
诊断
Cytomegalovirus
Fetus
Congenital infection
Prenatal diagnosis
