摘要
目的:探讨桥本甲状腺炎(HT)与甲状腺乳头状癌(PTC)的关系。方法:单纯HT73例,HT合并PTC23例,分析两者的临床表现、病理组织学表现,并作酪氨酸激酶受体(RET)免疫组化染色。结果:HT临床表现多样化,部分表现为结节状,合并的甲状腺癌均为乳头状癌,且微小癌占多数。50%HT病变对于RET染色存在局灶性阳性反应。结论:HT病变组织中不同程度地存在与PTC相同的肿瘤基因,HT合并的PTC可能与HT有关。
Objective To study the relationship between the Hashimoto's thyroiditis (HT) and the papillary thyroid carcinoma (PTC). Methods Seventy-seven cases with HT were studied, among whom 23 had PTC simultaneously. The clinical and pathological manifestation and RET immunohistochemical assay were carried out. Results The clinical re-presentations of HT were diverse, part of which were associated with nodules. The concomitant thyroid carcinoma was PTC, most of which in HT was the early tumor. Fifty percent of HT showed the focal positive expression under RET staining. Conclusions There exists the PTC oncogene products in the tissue of HT. PTC in HT may be associated with HT.
出处
《诊断学理论与实践》
2005年第1期12-16,共5页
Journal of Diagnostics Concepts & Practice
