1[1]Gary L. Johnson, Razvan Lapadat. The protein kinase complement of the human genome. Science, 2002;296(6): 1911 ~1912.
2[2]Walter Kolch. Meaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactions. J.Biochem., 2000; 351: 289~ 305.
3[3]Sun H., King A.J., Diaz, H.B., et al. Regulation of the protein kinase raf-1 by oncogenic ras through phosphatidylinositol 3- kinase, Cdc42/Rac and Pak. Curr. Bid.,2000; 10: 281~ 284.
4[4]King A.J., Sun H., Diaz, B., et al. The protein kinase Pak3 positively regulates Raf-1 activity through phosphorylation of serine 338. Nature, 1998; 396:180~ 183.
5[5]Maon C.S., Springer C.J., Cooper, R.G., et al. Serine and tyrosine phosphorylations cooperate in Raf-1, but not BRaf activation. EMBOJ., 1999; 18:2137~2148.
7[7]Scott T. Eblen, Jill K. Slack, Michael J., et al. Rac-PAK signaling stimulates exracellular signal-regulated kinase (ERK)activation by regulating formation of MEK1-ERK complexes.Molecular And Cellular Biology. 2002; 22(17): 6023~ 6033.
8[8]Andrei V., Khokhlatchev, Bertram Canagarajah, et al.Phosphorylation of the MAP kinase ERK2 promotes its homodimerization and nuclear translation. Cell, 1998; 93: 605 ~ 615
9[9]Mishima K, Inoue K, Hayashi Y. Overexpression of extracellular- signal regulated kinases on oral squamous cell carcinoma.Oral Oncol, 2002;38(5) :468~474.
10[10]Smalley KS. A piyotal role for ERK in the oncogenic behaviour of malignant melanoma. Int J Cancer, 2003; 104 ( 5 ):527~ 532.
二级参考文献8
1Koya D, King GL. Protein kinase C activation and development of diabetic complications [J]. Diabetes, 1998; 47 (12): 3
2Zheng CF, Guan KL. Cytoplasmic location of the mitogen activated protein kinase activater MEK [J]. J Biol Chem, 1994;269: 19947
3Haneda M, Araki S, Toyawa M, et al.MAP kinase cascade is activated in glomerular of diabetic rats and glomeruar mesangial cells in cultured under high glucose conditions [J]. Dabetes, 1997; 46:847
4Ingrom A, Ly H, Thai K, et al. Mesangial ccll signalling cascade in response to mechanical strain and glucose [ J ]. Kidney Inn, 1999; 56:1721
5Kang MJ, Wu X, Ly H, et al. Effect of glucose on stress - activated protein kinase activity in mesangial cells and diabetic glomeruli [J]. KidneyInt, 1999; 55:2203
6Tomlinson DR, Mitogen activated protein kinase as glucose transducers for diabetic complications [J]. Diabetologia, 1999; 42; 1271