2Smith WC,Harland RM.Expression cloning of Noggin,a new dorsalizing factor localized to the Spemann organizer in Xenopus embryos[J].Cell,1992,70(5):829~840.
3Valenzuela DM,Economides AN,Rojas E,et al.Identification of mammalian Noggin and its expression in the adult nervous system[J].J Neurosci,1995,15(9):6077~6084.
4Lamb TM,Knecht AK,Smith WC,et al.Neural induction by the secreted polypeptide Noggin[J].Science,1993,262(5134):713~718.
5McMahon JA,Takada S,Zimmerman LB,et al.Noggin-mediated antagonism of BMP signaling is required for growth and patterning of the neural tube and somite[J].Genes Dev,1998,12(10):1438~1452.
6Bachiller D,Klingensmith J,Kemp C,et al.The organizer factors Chordin and Noggin are required for mouse forebrain development[J].Nature,2000,403(6770):658~661.
8Zimmerman LB,De Jesus-Escobar JM,Harland RM.The Spemann organizer signal Noggin binds and inactivates bone morphogenetic protein 4[J].Cell,1996 ,86(4):599~606.
9Li W,LoTurco JJ.Noggin is a negative regulator of neuronal differentiation in developing neocortex[J].Dev Neurosci,2000,22(1~2):68~73.
1[1]Smith W C, Harland R M. Expression cloning of noggin, a new dorsalizing factor localized to the Spemann organizer in Xenopus embryos[J].Cell,1992,70(5):829-840.
2[2]Valenzuela D M,Economides A N,Rojas E,et al.Identification of mammalian noggin and its expression in the adult nervous system[J]. J Neurosci,1995,15(9): 6 077-6 084.
3[3]Lallier T E,DeSimone D W.Separation of neural induction and neurulation in Xenopus[J]. Dev Biol,2000,225(1):135-150.
4[4]McMahon J A,Takada S,Zimmerman L B,et al.Noggin-mediated antagonism of BMP signaling is required for growth and patterning of the neural tube and somite[J]. Genes Dev,1998,12(10):1 438-1 452.
5[5]Bachiller D,Klingensmith J,Kemp C,et al.The organizer factors Chordin and Noggin are required for mouse forebrain development[J]. Nature,2000,403(6 770):658-661.
6[6]Scott I C,Steiglitz B M,Clark T G,et al. Spatiotemporal expression patterns of mammalian chordin during postgastrulation embryogenesis and in postnatal brain[J]. Dev-Dyn, 2002,217(40):449-456.
7[7]Li W,LoTurco J J. Noggin is a negative regulator of neuronal differentiation in developing neocortex[J]. Dev Neurosci,2000,22(1-2):68-73.
8[8]Finley M F,Devata S,Huettner J E.BMP-4 inhibits neural differentiation of murine embryonic stem cells[J].J Neurobiol,1999,40(3): 271-287.
9[9]Soderstrom S,Ebendal T.Localized expression of BMP and GDF mRNA in the rodent brain[J].J Neurosci Res,1999,56(5):482-492.
10[10]Daniel A. Lim, Anthony D. Tramontin, Jose M. et al. Noggin antagonizes BMP signaling to create a niche for adult neurogenesis[J]. Neuron,2000,28(3):713-726.