摘要
支气管哮喘患者１０１例，随机双盲分为２组，沙美特罗组５２例（男性３４例，女性１８例；年龄３８±ｓ１０ａ），吸入沙美特罗５０μｇ，ｂｉｄ；相似患者４９例（男性３０例，女性１９例；年龄３８±９ａ），吸入沙丁胺醇２００μｇ，ｑｉｄ。２组治疗均４ｗｋ。结果显示沙美特罗组晨起最大呼气流速（ＰＥＦＲ）有显著改善（由２９６±８９Ｌ／ｍｉｎ增至３２１±１０２Ｌ／ｍｉｎ），提示沙美特罗作用时间较长，有助于对夜间哮喘的治疗。
One hundred and one patients with bronchial asthma were randomly divided into two groups in double-blind method.Group A(52 patients,M 34,F18;age 38±s 10 a)were treated with salmeterol aerosol 50 μg, bid for 4 wk.Other 49 similar patients group B(M 30, F 19; age 38±9 a) received salbutamol aerosol 200 μg,qid for 4 wk.Results showed improvement of morning PEFR from 296±89 L/min to 321±102 L/min (p<0.01)with long-acting control asthma in group A. It may be stated that salmeterol is useful for nocturnal asthma.
出处
《新药与临床》
CSCD
北大核心
1994年第6期322-324,共3页
