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两种方法检测血清C-反应蛋白含量的实验对比 被引量:5

The comparision of two methods of C-reactive protein measurement
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摘要 目的 评价免疫透射比浊法(ITD)和胶乳增强免疫透射比浊法(LEITD)检测C 反应蛋白(CRP)的可 靠性及临床应用。方法 分别对2种方法进行线性评价、精密度评价、干扰评价,并对二者相关性进行分析。结 果 2种方法线性范围均符合要求;LEITD精密度和抗干扰性较ITD好;2种方法有较好的相关性。结论 使用 LEITD检测CRP优于ITD。 Objective To evaluate the reliability and clinical application of measuring C-reactive protein (CRP) by immunoturbidimetric assay(ITD) and latex enhanced immunoturbidimetric assay (LEITD). Methods The linearity,precision,interference and reliabil between the two methods were analyzed. Results The linear ranges of their regression met the clinical needs.The precision of LEITD was better than that of ITD.The two methods had a fair correlation.LEITD was sensitive and less interfered than ITD. Conclusions Both methods can be used.LEITD is better than ITD.
出处 《检验医学》 CAS 北大核心 2005年第2期98-99,共2页 Laboratory Medicine
关键词 C-反应蛋白 免疫透射比浊法 胶乳增强免疫透射比浊法 精密度评价 线性分析 干扰实验 C-reactive protein Immunoturbidimetric assay Latex-enhanced immunoturbidimetric assay
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参考文献3

  • 1Yeh ET, Willerson JT. Coming of age of C-reactive protein using inflammation markers in cardiology[ J ]. Circulation ,2003,107:370-372.
  • 2De BK, Smith LG, Owen WE, et al. Performance characterisitics of an automated high-sensitivity C-reactive protein assay on the dimension RXL analyzer[J]. Clin Chem Acta,2002,323:151-155.
  • 3Roberts WL, Moulton L, Law TC, et al. Evaluation of nine automated high-sensitivity C-reactive protein methods: implications for clinical and epidemiological applications [J]. Part 2 Clinical Chemistry, 2001,47:418-425.

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