摘要
目的 探讨高敏C反应蛋白(hs- CRP)和心肌肌钙蛋白I(cTnI)浓度变化与冠状动脉(冠脉)的病变程度之间的关系。方法 冠脉造影患者按照造影结果分为阴性组、单支病变组、双支病变组和三支病变组,寻找hs -CRP和cTnI与冠脉病变的关系。结果 hs- CRP浓度按病变程度依次升高,双支病变组和三支病变组与阴性组比较差异有非常显著性(P<0. 001),cTnI的阳性率依次升高,差异有非常显著性(χ2 =50. 881,P<0. 001)。结论 血中hs CRP浓度的升高和cTnI阳性率的升高与冠脉病变的程度有着密切的联系,对冠心病的病变程度具有预测价值。
objective To evaluate the relationship between high-sensitivity C-reactive protein(Hs-CRP),cardiac troponin I(cTnI) and severity of coronary lesion.Methods The patients who were performed selective coronary angiography were divided into 4 gronps,The relationship between the hs-CRP,cTnI and severity of coronary lesion was observed.Results The hs-CRP levels in the 2-vessel lesion group and 3-vessel lesion group were significantly higher than those of normal control group (P<0.01),the positive rate of cTnI were significantly different among 4 groups(χ 2 =50.881,P<0.001).Conclusion The level of hs-CRP and cTnI is closely associated with heart disease and may be the predictor factor of patients condition in coronary artery disease.
出处
《临床内科杂志》
CAS
2005年第4期241-242,共2页
Journal of Clinical Internal Medicine
关键词
冠心病
C反应蛋白
心肌肌钙蛋白I
冠脉病变支数
Coronary artery disease
C-reactive protein
Cardiac troponin I
Number of diseased coronary vessels
