摘要
目的 探讨影响中央型肺癌经支气管动脉化疗栓塞远期疗效的相关因素。资料与方法 搜集1994年4月~1999年5月经介入治疗的中央型肺癌187例,其中生存3年以上有39例(A组) ,3年以下14 8例(B组)。对其临床资料进行对照分析。结果 A、B组中,发现肺癌多血供分别为10例、16例,采用综合治疗分别为35例、38例,介入化疗+栓塞分别为3例、5 8例,经χ2 检验,P <0 .0 5 ;A组中,Ⅳ期病例1例,介入治疗平均次数4 .3次/人;B组中,无Ⅱ期病例,介入治疗平均次数1.8次/人。结论 肿瘤的分期、供血情况、介入治疗方法等是影响中央型肺癌远期疗效的重要因素;早期诊治、寻找异位供血及综合治疗等是提高远期疗效的关键。
Objective To analyse related factor of long-term effect on central pulmonary cancinma by bronchial arterial infusion and embolization. Materials and Methods 187 cases with central pulmanary cancinma from April 1994 to May1999, including survive over three years 39 cases (A group) and under three years 148 cases(B group), were analysed retrospectively the affecting factors on long-term effect of central pulmanary cancer by interventional therapy. Results Among 187 cases,the 39 cases (A Ggrup) survived more than 3 years were in clinical stage Ⅱ-Ⅳ,the 148 cases (B Group) survived less than 3 years were in clinical stage Ⅲ-Ⅳ (no Ⅱ); 10 and 16 cases were rich on blood supply of tumor in group A and B respectively. 35 and 38 cases were treated by combined modality therapy in A and B groups, and 3, 58 cases were treated by interventional chemotherapy and embolization respectively. The A and B groups cases were treated through mean 4.3 and 1.8 times by interventional therapy.Conclusion Clinical tumor stage, blood supply of tumor, therapy project are the important factors on the long-term effect of central pulmanary cancer. Early diagnosis and treatment, finding ectopic blood supply and combined modality therapy are important to improve long-term effect.
出处
《临床放射学杂志》
CSCD
北大核心
2005年第4期354-356,共3页
Journal of Clinical Radiology