摘要
目的 研究妊娠期口服葡萄糖耐量试验(oral glucose tolerance test, OGTT)三次取血诊断妊娠期糖尿病(gestational diabetes mellitus, GDM)的可行性。 方法 对404例50 g葡萄糖负荷试验阳性的孕妇行 OGTT 检查。 结果 以美国糖尿病协会(American Diabetes Association,ADA)标准诊断 GDM者 111 例,葡萄糖耐量受损(impaired glucose tolerance test, IGT)者 72 例,OGTT正常者221例;若不计服糖后3 h血糖值,则诊断GDM者106例,IGT者71例,漏诊率分别为4.5%和1.4%。6 例漏诊孕妇与 OGTT正常的 50 g GCT阳性的 221 例孕妇相比,其妊高征、巨大儿、大于胎龄儿和Apgar评分≤3 分的发生率差异无统计学意义(16.6%和 8.1%、16.6%和 6.3%、50.1%和24.4%、0和0.9%,P均>0.05)。 结论 OGTT三次取血操作次数少、漏诊率低,临床上可作为GDM的诊断标准。
Objective To study the feasibility of ignoring the third-hour blood glucose value in oral glucose tolerance test(OGTT) in diagnosing gestational diabetes mellitus(GDM). Methods OGTT was performed in 404 pregnant women with the results of 50 g glucose challenge test(GCT) ≥7.8 mmol/L. Results Among the 404 pregnant women, 111 were diagnosed as GDM and 72 impaired glucose tolerance test (IGT) according to ADA criteria. The rest 221 pregnant women had normal OGTT results. In the event of ignoring the third-hour blood glucose level, 106 GDM and 71 IGT were diagnosed which meant that 4.5% of GDM and 1.4% of IGT were lost respectively. No significant difference was shown in the rate of pregnancy induced hypertension, macrosomia, large for gestational age infant and newborns with Apgar score≤3 between the 6 undiagnosed cases and the rest 221 cases with normal OGTT (16.6% vs 8.1%、16.6% vs 6.3%、50.0% vs 24.4%、0 vs 0.9%,P>(0.05,) respectively). Conclusions OGTT ignoring the third-hour plasma specimen is easy to be administered, has a low rate of undiagnosis and can be used in the diagnosis of GDM.
出处
《中华围产医学杂志》
CAS
2005年第2期89-91,共3页
Chinese Journal of Perinatal Medicine
