摘要
目的:研究前列腺增生组织中EGF、TGF-β1和iNOS表达及其临床意义。方法:应用免疫组化S-P法检测87例前列腺增生组织中EGF、TGF-β1和iNOS表达,并分析与临床化验指标和临床症状(前列腺液中白细胞计数、卵磷脂计数、尿频、尿痛和夜尿)的关系。结果:(1)87例前列腺增生组织中EGF、TGF-β1和iNOS表达的阳性检出率分别为63.2%(55/87)、47.1%(41/87)和56.3%(49/87)。(2)临床症状与EGF、TGF-β1、iNOS表达之间差异无统计学意义(P>0.05)。结论:(1)前列腺增生的发生发展与EGF、TGF-β1和iNOS表达有密切关系。(2)前列腺增生临床症状与EGF、TGFβ、iNOS表达关系不密切。
Objective: To investigate the expression of EGF, TGF-β1 and iNOS in prostatic hyperplasia and the relationship between clinical sings and their expression. Method: Specimens from 87 cases with prostatic hyperplasia were examined for EGF, TGF-β1 and iNOS by immunohistochemisry. And the results were analysed with the clinical signs. Result: (1)The positive frequency of expression of EGF, TGF-β1 and iNOS of tissues in 87 cases with prostatic hyperplasia was 63.2%(55/87), 47.1%(41/87) and 56.3% (49/87) respectivelg. (2)There is no difference between clinical sings and the expression (P>0.05). Conclusion: (1)It is suggested that the pathogen and development of prostatic plasia has a closed relationship with the expression of EGF, TGF-β1 and iNOS in prostatic hyperplasia. (2)There is not a closed relationship between clinical sings and the expression.
出处
《新疆医科大学学报》
CAS
2005年第4期366-368,共3页
Journal of Xinjiang Medical University
