摘要
目的 采用放射配体法检测118 例1 型糖尿病一级亲属的谷氨酸脱羧酶抗体(GA-DA)、蛋白酪氨酸磷酸酶抗体(IA-2A)、胰岛素自身抗体(IAA),发现三种抗体单独检出率与欧美高加索人接近,联合检测阳性率优于单一抗体检测。
In 118 first-degree relatives of patients with type 1 diabetes, the positive rates of the single assay of GADA, IA-2A and IAA were close to those of Caucasians and the positive rates of combined determinations of GADA, IA-2A and IAA were superior to those of single antibody testing.
基金
湖南省卫生厅重点资助项目(9736
2001 Z04)
卫生部优秀青年科技人才专项基金资助项目(Q9420)
国家自然科学基金资助项目(39370343)
关键词
1型糖尿病
GADA
IA-2A
IAA
抗体
特异性
Diabetes meilitus,type 1
First-degree relatives
Glutamic acid decarboxylase (autoantibody
) Protein tyrosine phosphatase autoantibody
Insulin autoantibody
