摘要
目的 探讨男性不育与常染色体异常的关系。方法 5 0 9例男性不育患者行外周血淋巴细胞G显带染色体核型分析。结果 在4 5 4例特发性生精异常患者中有2 3(5 .1% )例涉及常染色体结构异常,4 0 (8.8% )例涉及染色体多态性。结论 常染色体异常可以引起男性生精障碍。
Objective: This article is to analyze the relationship between abnormal autosomal karyotype and male infertility. Methods: Chromosomal karyotypes were examined in 509 male infertile patients by periphery blood lymphocyte culture and G banding. Results: The proportion of autosomal structure abnormalities was 5.1% (23/454) among the patients with idiopathic oligospermia and azoospermia, while that of chromosomal polymorphism was 8.8%(40/454). Conclusion: Autosomal berrations may result in spermatogenic arrest, which is one of the male infertile factors.
出处
《中国优生与遗传杂志》
2005年第5期46-47,44,共3页
Chinese Journal of Birth Health & Heredity
关键词
常染色体
男性不育
生精障碍
Abnormal autosomal karyotype
Male infertility
