摘要
目的探讨重症监护病房(ICU)死亡患者并发医院感染相关因素,以便采取有效控制措施. 方法对2000年12月～2003年12月,ICU住院时间>48h的 186例死亡患者进行医院感染的调查分析. 结果医院感染发生率为34.41%;死因与医院感染有关者占30.65%;感染部位以下呼吸道感染最多,占45.31%;感染病原体主要为条件致病菌,且多为多重耐药的致病菌;多因素Logistic回归分析提示泌尿道置管、气管切开、化疗、白细胞计数减少、抗生素预防性应用、持续意识障碍是发生医院感染的主要危险因素(P<0.05). 结论 ICU死亡患者医院感染发生率高,医院感染已成为危及患者生命的重要原因,应充分重视这些相关因素,予积极有效地防治措施,以减少医院感染的发生率,改善危重患者的预后.
OBJECTIVE To explore and control the related factors of nosocomial infection at ICU. METHODS A total of 186 cases died patients who had hospitalized over 48h in ICU of our hospital from Dec 2000 to Dec 2003 were retrospectively studied. RESULTS It was shown the nosocomial infected ratio was 34.41%. The number of those died patients whose death reason closely related with nosocomial infection occupied 30.65%. Lower respiratory tract infection was the highest (45.31%). Pathogenic bacteria were mostly the conditional ones, especially those with multidrug resistance. Multi-factorial Logistic regression analysis hinted that the urethra inserted tube, the trachea open, the chemotherapy, the white cell counts decrease, the antibiotic prophylaxis and keeping on the consciousness disorder were the main and dangerous factors to take place nosocomial infection (P<0.05) . CONCLUSIONS Our study clarifies that those died patients at ICU have a very high occurrence ratio of nosocomial infection, it means nosocomial infection has become to a deadly killer to critical patients. Those related factors to nosocomial infection should be paid great attention, and the positive and valid prevention and cure measures should be taken, it will be valuably to reduce the occurrence ratio of nosocomial infection, and improve the critical patients' recovery.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2005年第6期622-625,共4页
Chinese Journal of Nosocomiology
