摘要
对脂质体与表皮角质层的作用作了综述。脂质体能增加角质层的含水量及水合作用,并与角质细胞间的脂质结合,可以削弱表皮角质层的屏障功能,促进透皮吸收。
The interaction between liposome and horny layer and update results obtained both in vitro and in clinical studies are reviewed. Liposome may increase humidity and hydration in horny layer as well as integration into the intercellular lipid of corny layer so as to decrease the barrier function of horny layer of epidermis,and promote transdermal absorption of drugs.
出处
《中国医药工业杂志》
CAS
CSCD
北大核心
1994年第11期522-525,共4页
Chinese Journal of Pharmaceuticals
关键词
脂质体
透皮给药系统
透皮吸收
liposome
transdermal drug delivery system
percutaneous absorption