摘要
西洋参茎叶皂甙（０．０３～３ｍｇ／ｍｌ）可抑制豚鼠乳头肌缩力，对高钾去极化标本，西洋参茎叶皂甙（０．０３～０．３ｍｇ／ｍｌ）可使缩力增加。西洋参单体皂甙－Ｒｅ１０ｍｇ／ｋｇ，－Ｒｂ＿３３０ｍｇ／ｋｇ可抑制大鼠血流动力学ＬＶＳＰ，土ｄｐ／ｄｔｍａｘ等指标，单体Ｐ－Ｆ＿（１１）１０ｍｇ／ｋｇ与上述作用相反。证明西洋参茎叶皂甙中存在作用相反的成分。
xperiments have shown that PQS(0.03～3mg /ml)can
inhibit the contractility of papillary muscle of guineapigs,and on
depolarized sample of papillary,muscle with high potassium,PQS(0.03～
0.3mg/ml)can increase this con-tractility,Monomer
saponin-Re(10mg/kg),-Rb_3(30mg/kg)can inhibit the hemodynamic
indication of rats,but pseu-dogisenoside-F_(11)( 1 0mg/kg)acts the
other way round.These results prove that PQS contains two components
ofopposite actions。
出处
《中国中药杂志》
CAS
CSCD
北大核心
1994年第10期617-620,共4页
China Journal of Chinese Materia Medica
关键词
西洋参
茎
叶
皂甙
大鼠
电刺激
心脏
PQS
monomer ginsenoside
papillary muscle
of guinea pig
hemodynamic indication of rat
electricalstimulation
