摘要
研究加味己椒苈黄汤对慢性阻塞性肺疾病肺动脉高压患者肺动脉平均压的影响。60例慢性阻塞性肺疾病(COPD)肾阳虚同时伴有肺动脉平均压升高患者,随机分为加味己椒苈黄汤治疗组和硝苯地平对照组(各30例),治疗14天,观察临床总有效率、临床症状积分、肺动脉平均压、肺功能等指标及不良反应。结果:治疗组总有效率为86. 67%,明显高于对照组总有效率40% (P<0 01);两组均能明显降低COPD伴肺动脉高压患者的肺动脉平均压(P<0. 01),且治疗组优于对照组(P<0. 05);但是对肺功能的改善两组都不明显(P>0. 05)。结论:中药加味己椒苈黄汤治疗慢性阻塞性肺疾病肺动脉高压具有良好的疗效,其作用优于硝苯地平。
To study the effects of “Jijiao Lihuang Decoction” on the average pulmonary pressure of chronic obstructive pulmonary disease(COPD) with pulmonary hypertension of kidney yang deficiency, 60 subjects were randomized into two groups: treatment group in which 30 cases were treated with this Decoction and control group in which another 30 cases were treated with nifedipine, with a course of 14 days. The total effective rate, clinical symptom score, average pulmonary pressure and lung function were observed. Results: The total effective rate was 86.67% in treatment group, higher than 40.00% in control group ( P <0.01); in both groups, the average pulmonary pressure dropped ( P <0.01), with more obvious drop in treatment group than in control group ( P <0.05), but the lung functions improved little( P >0.05). Conclusion: This Decoction has better effect on pulmonary hypertension than nifedipine.
出处
《上海中医药杂志》
北大核心
2005年第6期24-25,共2页
Shanghai Journal of Traditional Chinese Medicine
基金
上海市卫生局基金资助项目(00-9-05)。
关键词
加味己椒苈黄汤
肾阳虚
慢性阻塞性肺疾病
肺动脉高压
肺动脉平均压
Jijiao Lihuang Decoction”
kidney yang deficiency
chronic obstructive pulmonary disease
pulmonary hypertension
average pulmonary pressure
