摘要
对血请前列腺特异性抗原（ＰＳＡ）高于４μｇ／Ｌ，且有病理检查资料的６７例前列腺疾病患者，进行了分析。其中前列腺癌２４例，非癌前列腺病变４３例。结果显示前列腺癌组血清ＰＳＡ明显高于非癌组（Ｐ＜０．０１）。以血清ＰＳＡ１０μｇ／Ｌ为低限值，诊断癌的灵敏性为８３．３％。特异性为７４．４％，认为血请ＰＳＡ４～１０μｇ／Ｌ应视为癌的危险范围。
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patients with serum prostate specific antigen(PSA) over 4ng / ml were investigated
pathologically.All the patients had prostatic lesions: prostate cancer(24) and benign prostatic
lesions (43). The serum PSAwas conspicuously higher in the carcinoma group thanin the benign
group (P<0.01). When 10ng / ml wasused as the low limit to detect prostate cancer, the
sen-sitivity and specificity were 83.3% and 74.4%respectively. We suggest that the range of
serum PSAfrom 4.0 to 10.0ng / ml should be considered danger-ous in detecting prostate
cancer. The epi-thelium-blood barrier lesion and epithelialhyperplasia of the prostate might be
the pathologicalbasis for the elevation of serum PSA.
出处
《中华医学杂志》
CAS
CSCD
北大核心
1994年第5期306-308,共3页
National Medical Journal of China
基金
国家自然科学基金
关键词
前列腺肿瘤
前列腺疾病
免疫反应
Prostaic neoplasms
ProstatesAntigenic determinants Serology Pathology
