摘要
在显微电视放大500倍条件下,对虎杖4号于大鼠移植岛状皮瓣在静脉阻断6小时再通后微循环变化的影响,借助计算机图像分析系统进行直接动态观察,并结合组织学检查及皮瓣7天成活率的观测。结果表明,虎杖4号可明显提高皮瓣局部血液灌注量、血流速度,增加毛细血管开放面积,减少血栓形成及提高血管内皮细胞对缺血、缺氧损伤的耐受能力,从而提高了皮瓣成活率。实验还表明,术前开始及术后开始用药组效果接近。
The effects of crystal No.4 of Polygonum cuspidatum on microcirculatory changes of island flaps in rats following resumption of blood flow after venous occlusion of six hours were observed with a special TV set with magnification of 500X.The pathological events and survival rate of flaps were recorded as well.The results showed that the survival rate,amount of open capillaries,amount of blood flow,and velocity of blood flow of flaps treated by crystal No.4 of polygonum cuspidatum were much higher than those of untreated control flaps.The white thrombosis and endothelial damage of dermal vessels were alleviated by administration of crystal No.4 of polygonunm cuspsidatum.The experiment also showed that there were no differences between flaps treated with crystal No.4 of polygonum cuspi- datum preoperatively and flaps treated with it postoperatively.
关键词
虎杖
皮瓣
微循环
Crystal No.4 of Polygonum cuspidatum
Island flap
Microcirculation
