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4种药物联合治疗消化性溃疡的临床研究

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摘要 目的:研究猴头菌颗粒、埃索美拉唑(Esomeprazole)、羟氨苄青霉素、克拉霉素联合对消化性溃疡的治疗应用价值。方法:选取本院门诊消化性溃疡患者53例,随机分为两组:治疗组27例,为猴头菌颗粒、埃索美拉唑、羟氨苄青霉素、克拉霉素四联合用药治疗1周后,再继续用猴头菌颗粒治疗3周。对照组26例,为奥美拉唑,羟氨苄青霉素、克拉霉素三联合用药治疗4周。结果:对消化性溃疡治愈率:治疗组为92.6%,对照组为92.3%,治愈率差别均无显著性(P>0.05),对幽门螺杆菌(Hp)的根除率:治疗组为92.6%,对照组为92.3%,两组差别无显著性(P>0.05)。结论:四联合用,使胃内pH>4的时间更长,增强抗Hp的作用和改善胃黏膜营养状态,促进胃黏膜细胞再生。对Hp的根除作用及其对溃疡愈合率均较理想,达到了临床较理想的效果。
出处 《实用医技杂志》 2005年第05B期1301-1302,共2页 Journal of Practical Medical Techniques
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参考文献4

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