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急性主动脉夹层分离C反应蛋白浓度变化的临床意义 被引量:10

Significance of the level of C -reactive protein in acute aortic dissection
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摘要 目的:探讨急性主动脉夹层分离(acute aortic dissection,AAD)患者血清C反应蛋白(C-reactive protein, CPR)水平与病情程度及预后的关系。方法:测定44例AAD患者血清CRP浓度,根据血清CRP增高的程度和持续时间将44例患者分为A、B两组。A组:26例,CRP峰值≥30 mg/L且持续≥两天;B:组18例,CRP<30 mg/L, 其中有2例CRP峰值>30 mg/L,但持续少于两天。分析血清CPR浓度与病情程度及预后的关系。结果:44例AAD 患者CPR浓度均增高,A组中发生夹层继续分离及住院期间死亡率明显高于B组(30.7%对5.5%和23.1%对0%), 差异有显著性(P<0.05)。结论:急性主动脉夹层分离患者血清中的CPR含量与病情程度及预后有关。 Objective: To investigate the relationship among the levels of C-reactive protein (CRP) and the serious extent, prognosis of acute aortic dissection (AAD). Methods:The serum levels of CRP were measured in 44 A AD cases. According to the level and lasting period of CRP, the patients were divided into groups; group A (CRP≥30 mg/L,n = 26) and group B(CRP<30 mg/L,n= 18). The serious extent of the disease and cardiovascular evenis were compared between two groups. Results: All the patients have high levels of CRP. The incidences of lasting aortic dissection were higher in group A compared with that of group B (30. 7% vs 5. 5% , P<0. 05). The mortality of group A was higher than that in group B(23. 1% vs 0% ,P<0. 05). Conclusion:The lasting and higher levels of CRP predict the increase risk of bad prognosis in acute aortic dissection.
作者 王淑红
出处 《心血管康复医学杂志》 CAS 2005年第3期224-225,共2页 Chinese Journal of Cardiovascular Rehabilitation Medicine
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