摘要
目的探讨胃肠道外MALT淋巴瘤临床病理特点。方法复习14例胃肠道外MALT淋巴瘤临床病理资料及病理切片。结果胃肠道外MALT淋巴瘤占MALT淋巴瘤的42.42%,发病中位年龄为50岁,85.71%为AnnArborⅠ期,42.86%发生于眼部。肿瘤细胞以边缘区B细胞样细胞为主,伴有少量免疫母细胞样细胞及浆细胞,1例可见大细胞转化区。随访11例,10例存活,1例死亡。结论胃肠道外MALT淋巴瘤患者发病年龄较胃肠道患者年龄小,好发于眼部,较少向大细胞淋巴瘤转化。
Objective: ?To study the clinicopathological features of nongastrointestinal MALT lymphoma. Methods: ?14 cases of MALT lymphoma were analyzed retrospectively. Results: ?Among the 14 cases of MALT lymphoma,42.42% were of nongastrointestinal origin.The median age was 50 years old.85.71% of the 14 cases were Ann Arbor stage Ⅰ,42.86% were confined to the eyes.Morphologically the tumors were mainly composed of marginal zone B cells with a few immunoblast cells and plasma cells.Transforming to large cell lymphoma was observed in one of the cases.Eleven of the 14 case were followed up of which ten survived and one died. Conclusion: ?The patients with nongastrointestinal MALT lymphoma are younger than those with gastrointestinal one and have good prognosis.It is likely to occur in eyes and rarely transforms to large B cell lymphoma. [
出处
《四川肿瘤防治》
2005年第2期73-74,共2页
Sichuan Journal of Cancer Control
