摘要
目的了解深圳地区献血人群中弓形虫感染和分布情况。为医疗安全用血提供科学依据。方法采用酶联法(ELISA)检测标本血清中弓形虫的IgG、IgM,初筛检测阳性,复查仍为阳性,判断为阳性。结果对随机抽取的680例无偿献血者进行检测,检出IgG阳性为49例,IgG阳性率为7.21%;IgM阳性2例,IgM阳性率为0.29%。其中18～30岁、31～40岁、41～55岁IgG阳性率分别为5.91%、7.04%和9.26%;在校大学生、外来打工人员、家庭妇女、公务员及企业职员阳性率分别为6.57%、6.98%、11.2%和6.12%;男性、女性IgG阳性率分别为7.6%、6.62%。结论献血者人群中弓形虫感染率随着年龄的增长有增高的趋势;家庭妇女组的阳性率高于其他3组人群;男女人群的阳性率差异无显著性。对于感染弓形虫的献血者存在潜在的输血传播该病的可能性应起重视。
Objective To investigate the morbidity and distribution of blood donors with positive Toxoplasma gondii IgG and IgM antibody (PTA) for the evidence base of Toxoplasma gondii assay in the donor population of Shenzhen District. Methods The Toxoplasma gondii IgG and IgM antibody (PTA) of serum samples were assayed by ELISA method. If the serum sample was PTA with first assay, it will be measured again. If the serum sample was still positive, the donor will be considered as positive one. Results 680 cases of donors had been randomly selected for assay of Toxoplama gondii IgG and IgM antibody. 49 cases were IgG antibody positive with a positive rate of 7.21 %; 2 cases were IgM antibody positive with a positive rate of 0.29%. The positive IgG rates were 5.91%, 7.04% and 9.26% in age groups of 18～30, 31～40 and 41～55, respectively. The IgG positive rates were 6.57%, 6.98%, 11.2% and 6.12% in college students, workers from outside of Shenzhen, family women, cardres and professionals, respectively. The IgG positive rates were 7.6 % and 6.62% in male and female donors, respectively. Conclusion The IgG positive rates in donors were elevated as their age increased. The IgG positive rate in family women was higher than other three groups. There was no significant difference between the IgG positive rates in male and female donors. The results suggest that there are the donors with PTA , which could result in potential infection of toxoplamosis in blood transfusion.
出处
《中国热带医学》
CAS
2005年第3期599-600,638,共3页
China Tropical Medicine
