摘要
目的评价加替沙星临床疗效及其应用的安全性。方法收集加替沙星治疗呼吸道感染、泌尿道感染、外科感染、皮肤软组织及耳鼻喉科感染病例466例,采用加替沙星治疗,0.4g/d,静脉滴注,疗程7~14天,对其临床疗效、不良反应及细菌学方面进行评价。结果466例细菌感染患者中总有效率为90.12%,细菌清除率为92.17%、不良反应发生率为3.73%。结论加替沙星是一种安全、有效的氟喹诺酮抗菌药物。
Objective To evaluate clinical efficacy and safety of gatifloxacin. Methods Collecting 456 patients with respiratory tract infections , urinary tract infections , surgical infections , skin and soft tissue infections , and otolaryngology infections treated by gatifloxacin injection for 7~14days with 0.4g, iv, gtt, qd, evaluating therapeutic efficacy, adverse rates and bacteriology. Results The total effective rates was 90.12%, the bacterial clearance rates was 92.17%, the adverse reaction rates was 3.73%.Conclusion Gatifloxacin is an effective and safe antibacterial drug of the fluorinated-quinolones.
出处
《医药论坛杂志》
2005年第13期46-47,共2页
Journal of Medical Forum
关键词
加替沙星
感染
临床疗效评价
不良反应
Gatifloxacin
Infection
Clinical efficacy
Adverse reaction