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异丙酚用于无痛苦纤维支气管镜检的效果观察 被引量:5

Application of Propofol in Painless Fibrobronchoscopy and Its Effects
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摘要 目的:评价异丙酚静脉全身麻醉,减轻纤维支气管镜检查痛苦的效果。方法:将160例接受纤维支气管镜检患者随机分为异丙酚组和对照组。异丙酚组90例,给予剂量为1.5mg/kg、静脉注射速度为30mg/10s的异丙酚麻醉后镜检;对照组70例,行常规纤维支气管镜检。结果:异丙酚静脉注射后平均(40.73±7.91)s出现睫毛反射消失,停止注射药物后平均(5.39±1.85)min出现唤醒反应,完全清醒时间为(10.82±2.73)min。异丙酚组未见血压明显改变、心肌缺血和心律紊乱,术后满意率为96%,患者愿意接受第2次纤维支气管镜检;对照组患者进镜后明显出现咳嗽、挣扎,术后满意率为81%,20%的患者拒绝接受第2次纤维支气管镜检。结论:异丙酚用于无痛苦纤维支气管镜检安全、有效。 OBJECTIVE:To evaluate the effects of propofol in relieving pain during fibrobronchoscopy when it is used in general intravenous anesthesia.METHODS:160patients undergoing fibrobronchoscopy were randomly divided into propofol group and control group.90patients in the propofol group were anesthetized intravenously by injection of propofol at the dosage of1.5mg/kg and speed of30mg/10s and then underwent fibrobronchoscopy;While70patients in the control group underwent regular fibrobronchoscopy.RESULTS:The lash reflex disappeared within(40.73±7.91)seconds after propofol injection,and patients became conscious within(5.39±1.85)minutes after stopping injection,full consciousness occurred at(10.82±2.73)minutes.Electrocardiogram did not show any signs of change in blood pressure,myocardial ischemia and cardiac dysrhythmia,the post-operative satisfaction rate was96%as compared with81%in the control group.The patients in the propofol group showed extensive willingness for second fibrobronchoscopy,while the patients in the control group presented cough,struggle,and20%of them refused the second fibrobronchoscopy.CONCLUSION:It is safe and effective to apply propofol in painless fibrobronchoscopy.
出处 《中国药房》 CAS CSCD 北大核心 2005年第14期1094-1095,共2页 China Pharmacy
关键词 异丙酚 静脉麻醉 纤维支气管镜 Propofol Intravenous anesthesia Fibrobronchoscope
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参考文献2

  • 1Koshy G, Nair S, Nokus EP, et al. Propofol versus midazolam and meperdine for conscious sedation in GI endoscopy[J]. Am J Gastroenterol, 2000, 95( 6): 1 476.
  • 2Wehrmann T, Kokabpick S, lembcke B, et al. Efficacy and safety of intravenous propofol sedation during roution ERCP: a prospective, controlled study[J]. Gastrointest Endosc, 1999, 49( 6): 677.

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