摘要
目的:了解潜伏梅毒患者及其性伴在临床表现和血清学方面的异同.方法:对40例潜伏梅毒患者及其性伴进行了临床特点和血清学的分析.结果:潜伏梅毒患者女性明显高于男性;由于性伴检测出梅毒而追踪发现的仅有15例,占27.3%,40例潜伏梅毒患者中,血清RPR滴度介于1:1～1:128之间.40例性伴中,15例确诊为潜伏梅毒,5例为显性梅毒,血清RPR滴度介于1:16～1:64之间.治疗后6个月与治疗后3个月的RPR转阴率无显著差异(χ2=0.0518,P＞0.05),而治疗后6个月与治疗后3个月的IgM转阴率有显著差异(x2=3.9759,P＜0.05).结论:必须注重对潜伏梅毒患者的筛查和性伴的追踪检查,同时对确诊患者进行血清学的评估和治疗,对减少梅毒的发病率和降低感染艾滋病的风险有很重要的现实意义.
Objective: To compare the clinical and serologic differences between the patients with latent syphilis and their sex partners. Methods: Forty patients with latent syphilis and their sex partners were analyzed in clinical features and serologically. Results: There were more female with latent syphilis in this group of patients. Only 15(27.3%) cases were discovered through contact tracing after the index patients were diagnosed having syphilis. The titers of RPR were between 1:1 and 1:128 among the 40 patients with latent syphilis. Out of 40 sex partners, latent syphilis was found in 15. Of the 15 patients 5 were apparent syphilis with the titers of RPR between 1:1 and 1:64. Compared with pre-therapy, the RPR negative converse rate did not significantly decreased at month 6 after treatment (χ~2=0.0518,P>0.05), but the difference in IgM negative converse rate was significant at month 6 after the treatment. (χ~2=3.9759,P<0.05). Conclusion: Screening of latent syphilis and sex partner tracing for the index syphilis patients should be emphasized. At the same time, serological evaluation of the therapeutic results for the diagnosed syphilis patients may have an important value not only in reducing the incidence of syphilis, but also in reducing the risk in getting HIV infection.
出处
《中国麻风皮肤病杂志》
2005年第7期518-520,共3页
China Journal of Leprosy and Skin Diseases
