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三黄合剂抑制血小板聚集作用的临床与实验研究 被引量:6

Clinical and Experimental Study on Inhibitory Effect of Sanhuang Mixture on Platelet Aggregation
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摘要 三黄合剂(心脉胶囊)由黄芪、黄连、黄苓三味药组成。它对大鼠ADP诱导的血小板聚集有抑制作用,在人体外试验中能抑制ADP、ADR诱导的血小板聚集。心脉胶囊治疗血小板高聚集率患者的有效率为88.7%,与肠溶阿司匹林50mg/d的疗效相当。中医辨证分型各组疗效以气虚血瘀型最高(92.3%),瘀痰互结型最低(72.7%)。 Sanhuang mixture(Xinmai capsule) is composed of Astragalus membranaceus,Coptis chinensis and Scutellaria baicalensis.It could inhibit platelet aggregation(PAG) induced by ADP in rats or by ADP and ADR in vivo.Patients with high PAG took Xinmai capsule for 4 weeks,the effective rate was 88.7%,which was same as the efficacy of aspirin 50mg/day.In Syndrome Differentiation of TCM,the effective rate was the highest(92.3%) in the Syndrome of Qi Deficientcy-Blood Stasis, and the lowest(72.7%) in the Syndrome of Stasis Phlegm and combined together.
出处 《中国中西医结合杂志》 CAS CSCD 北大核心 1995年第8期465-467,共3页 Chinese Journal of Integrated Traditional and Western Medicine
关键词 三黄合剂 肠溶阿司匹林 血小板聚集 实验 Sanhuang mixture (Xinmai capsule),aspirin, platelet aggregation
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参考文献3

  • 1小儿血瘀证诊断标准(试行方案)[J]中国中西医结合杂志,2000(02).
  • 2乐兆升,刘娴芳,孙颖立,廖家祯,姚素珍,李英麟,陈信义,方来刚.53种中草药抗血小板聚集作用的初步观察[J]中药通报,1985(01).
  • 3于世增,王永红.补阳还五汤和黄芪对血小板聚集性的影响[J]中成药研究,1983(08).

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