摘要
目的探讨急性有机磷农药中毒患者尿转铁蛋白检测的意义。方法用速率散射比浊法检测71例急性有机磷农药中毒患者尿转铁蛋白,并与45例正常对照比较。结果71例急性有机磷农药中毒患者中20例中毒后尿转铁蛋白逐渐增高,随着病情的发展尿蛋白阳性。51例尿蛋白阴性中毒患者尿转铁蛋白增高20例,在中毒后第1、3、5、7天尿转铁蛋白中位数分别为108.2mg/molCr及213.6mg/mol Cr、90.3mg/mol Cr及62.6mg/mol Cr,均高于正常对照51.2mg/mol Cr,差异有显著性(P<0.05),且中毒愈重,尿转铁蛋白增高愈明显。结论尿转铁蛋白检测对急性有机磷农药中毒患者早期肾损害的诊断具有重要意义。
Objective To explore significance of urinary transferrin detection in acute organophosphorus pesticide poisoning.Methods Testing urinary transferrin with rate scatter nephelometry in 71 patients with acute organophosphorus pesticide poisoning, and compared with 45 cases of normal control.Results Out of 71 patients with acute organophosphorus pesticide poisoning,20 patients′ urinary transferrin was higher and urinary albumen was positive with the development of disease. 20 patients′ urinary transferrin was higher in 51 patients with urinary albumen negative, results of urinaty transferrin median were 108.2,213.6,90.3,62.6mg/mol Cr on day1,day3,day5,day7 respectively after poisoning,higher than that of normal control (51.2mg/mol Cr),difference was more significant (P< 0.05 ),the more poisoning ,the higher of urinary transferrin.Conclusion Urinary transferrin detection may play a role in the early diagnosis in kidney damage of acute organophosphorus pesticide poisoning.
出处
《国外医学（临床生物化学与检验学分册）》
2005年第7期420-421,共2页
Foreign Medical Sciences(section of Clinical Biochemistry and Laboratory Medicine
