摘要
采用改良的Ａｌｅｎ法打击猫脊髓致伤模型，测定伤后２小时～１周伤区及邻近脊髓组织血小板活化因子（ＰＡＦ）含量及水含量。结果表明，伤后２～７２小时伤区及邻近脊髓组织ＰＡＦ含量及水含量较对照组明显增高（Ｐ＜０．０１），而伤后１周时与对照组无显著性差异（Ｐ＞０．０５）。提示ＰＡＦ在脊髓损伤后脊髓水肿的发生、发展过程中起重要作用。
Spinal cord contussion in cats was made by Allen's improved method. Platelet active factor (PAF) levels and water content in injured spinal cord tissue and adjacent spinal cord tissue to the injured were measured from 2 hours to 1 week after spinal cord injury. The results showed that PAF levels and water content in the injured spinal cord tissue and the adjacent spinal cord tissue increased significantly in 2 to 72 hours after trauma as compared to the control group ( P <0.01). PAF levels and water content in the adjacent spinal cord tissue had no significant difference between 1 week after trauma group and the control group ( P >0.05). It is considered that PAF plays an important role in production and development of spinal cord edema after trauma. (Original article on page 332)
出处
《中华创伤杂志》
CAS
CSCD
北大核心
1995年第6期332-334,共3页
Chinese Journal of Trauma
关键词
脊髓损伤
脊髓水肿
血小板活化因子
Spinal cord injury Spinal cord edema Platelet active factor
