摘要
超临界反溶剂过程是近年来提出的一种制备纳微米粉体材料的新方法。应用超临界反溶剂过程实验装置制备银杏提取物(GBE)超细微粒,实验中以乙醇为溶剂,超临界CO2为反溶剂,制备出平均直径在1μm至2μm范围内的GBE超细微粒。同时研究了操作压力、操作温度及二氧化碳与溶液流率比等操作参数对制备的超细微粒粒径、形态及粒径分布的影响。实验结果表明:操作压力、温度对制备的GBE微粒影响较为显著。
The supercritical antisolvent (SAS) process apparatus for conducting the experiments of producing the micro- and nano-GBE particles were established. With the apparatus, the effects of pressure, temperature and flow ratio of CO2 to the solution on the shape and size of the precipitated particles from the GBE-ethanol-CO2 system were studied. The experimental results show that the GBE microparticles with diamiters ranging form 1 μm to 2 μm can be obtained by SAS process with ethanol as solvent. The most effective factor effecting on the shape and size of the precipitated particles is pressure, the next is temperature and the least is the flow ratio of CO2 to solution.
出处
《高校化学工程学报》
EI
CAS
CSCD
北大核心
2005年第4期550-553,共4页
Journal of Chemical Engineering of Chinese Universities
基金
国家自然科学基金(20176003)。
关键词
超临界反溶剂过程
银杏提取物
超细颗粒
粒径
粒径分布
Carbon dioxide
Ethanol
Extraction
Particle size analysis
Precipitation (chemical)
Solvents
