摘要
对１４２例癫痫病人进行间歇期ＳＰＥＣＴ局部脑血流显像，并与脑ＣＴ、ＭＲＩ、ＥＥＧ、皮质脑电图（ＥＣｏＧ）及手术病理结果进行比较。结果表明，ＳＰＥＣＴ阳性率最高（７５．４％），ＣＴ和ＭＲＩ分别为５２．０％和５６．７％．ＳＰＥＣＴ能准确定位癫痫灶，与埋藏式ＥＣｏＧ或术中ＥＣｏＧ标测结果（ｎ＝５１）的符合率达９２．０％。致痫灶的病理改变多为隐匿性脑血管畸形、胶质增生、局灶性神经元固缩、变性及排列紊乱等。研究表明ＳＰＥＣＴ局部脑血流显像是诊断癫痫病灶的有效方法，灵敏度优于ＣＴ和ＭＲＩ，定位价值优于ＥＥＧ，对于制订癫痫的手术治疗方案有一定帮助。
Abstract rCBF brain SPECT with 99mTc-ECD was performed on 142 patients with interical epilepsy and was compared with X-ray CT,MRI, electroencephalogram(EEG),electrocorticoencephalogram(ECoG) and pathological findings.with invasive ECoG monitoring or mapping was in concordance with brain SPECT in 46/50(92.0%)patients.The pathological findings of tissue samples commonly involved occult vascular malformation,gliosis or focal neurone lesions.Thereby we concluded that rCBF brain SPECT may haw some advantage in detecting and localizing epileptic foci and it may be also helpful in preparing a reasonable operative protocol for a special epileptic patient.
出处
《中华核医学杂志》
CSCD
北大核心
1995年第2期69-71,共3页
Chinese Journal of Nuclear Medicine
