摘要
作者对１８０例冠心病病人球结膜微循环进行了观察，发现有微血栓者占２３．９％。分阶段地将有微血栓、无微血栓的冠心病病人及正常人王者进行对照，并对有微血栓的冠心病病人作了肝素或丹参治疗前后的对比观察。发现冠心病病人微血栓的有无、数量多寡及易否消散，与症状、心电图、血栓素Ｂ２（ＴＸＢ２）、６－酮－前列腺素Ｆ１ａ及血液流变学改变等关系密切。微血栓长期不消散者，猝死率明显增高。认为可将微血栓作为冠心病病人病情变化、疗效观察及预后判断的一项重要指标。微循环中出现微血栓是使用肝素治疗的重要指征。
f 180 patietns with coronary heart disease (CHD)43
(23. 9 %) showed in microthrombi coujunctival mi-crocirculation. We compared the healthy
subjects withthe patients with microthrombi and thrombi-free as wellas with the patients with
microthrombi pre and post-treatment of heparin or salvia mihiorrhizae. The forma-tion and the
number of microthrombi in the CHD pa-tients were closely related to symptonis, ECGS,
plasmaTXB2, 6-kero-PGFla and other indexes on hemody-namics. Followup of the patients with
microthrornbi re-vealed that their death rate was higher than that ofCHD patients without
microthrombi, especially in thesudden deaths. We consider that microthrornbi may beregarded
as an important index of the state. therapeuticefficacy, and prognosis of the CHD patients. The
use ofheparin niay certainly be based on the condition of themicrothrombi in the
microcirculation of CHD patients.
出处
《中华医学杂志》
CAS
CSCD
北大核心
1995年第5期266-269,共4页
National Medical Journal of China
关键词
冠状动脉疾病
结膜
微循环
血栓
诊断
冠心病
Coronary heart disease Conjuncti-va Microcirculation
Microt Thrombi
