摘要
本文报导了合锌量不同的饲料对15％体表面积(BSA)Ⅲ°烧伤的大耳白兔烧伤愈合的影响。18只雄性成年家兔在低锌饲料饲喂2周后,血清锌显著下降;烧伤后血清锌进一步降低,并一直未恢复到正常水平。而补锌组血清锌迅速回升到正常范围。血清碱性磷酸酶(AKP)活力的变化与血清锌相同,两者呈高度相关。高锌组烧伤愈合的时间显著快于低锌组。结果表明,锌可以促进烧伤愈合,并提示血清AKP活力可作为烧伤后低锌血症的诊断和补锌效果观察的指标。
We report herein the effects of varying dietary zinc contents on burns healing in 15% body surface area (BSA) Ⅲ° burned Lop rabbits. 18 adult male rabbits were given a low zinc diet for two weeks, resulting in a decrease of serum zinc concentration which further decreased postburn without restoration. On the contrary, serum was restored rapidly to normal levels in the zinc supplemented groups. Similar changes were found in serum alkaline phosphatase (AKP) activity, and there was a close relationship between serum zinc and serum AKP activity. Burns healing in the high zinc group was markedly faster than that in the low zinc group. These results strongly suggested that zinc might be a factor benefiting burns healing. We concluded that serum AKP activity could be used as a diagnostic criterion of postburn hypozincemia as well as a valid index in the assessment of the effectiveness of supplemented zinc.
出处
《营养学报》
CAS
CSCD
北大核心
1989年第1期54-59,共6页
Acta Nutrimenta Sinica
关键词
烧伤
家兔
低锌血症
碱性磷酸酶
burns rabbit hypozincemia alkaline phosphatase
