摘要
首次将连串反应用于速差动力学分析,测定了具有广泛生物活性的肾上腺素和去甲肾上腺素的含量、对于连串反应A(?)B(?)C,由于动力学方程与两个速率常数k_1和k_2有关,混合体系的K_1或者k_2有差异,都能用于速差动力学分析,这与利用简单反应进行速差动力学分析有所不同,为提高速差提供了更多的可能性.三-(1、10-邻菲啰啉)-铁(Ⅲ)配合物氧化肾上腺素或去甲肾上腺素的过程为一连串反应,两者的k_1相近而k_2差异显著,利用k_2的差异可以进行两者的同时测定.对于10^(-5)mol·dm^(-3)级的肾上腺素-去甲肾上腺素混和物,比例范围在1:6.88到2.91:1之间,测定误差小于±5%,平均精密度为2.5%.
For the first time, successive reactions was used in differential kinetic analysis, and simultaneous determination of epinephrine and norepinephrine based on it was carried out. For sue-cessive reaction A k1Bk2C, because the integral kinetic equation have relationship with tworate constants k1, and k2, two rate constants can be used in differential kinetic analysis, this afford more possibility to increase the kinetic difference between mixed species. The successive reaction between tris(1,10-phenanthroline)-iron(Ⅲ) and epinephrine or norepinephrine was investigated, it was found that between the two species, k1 was similar, but k2 had enough difference, this was exploited by conventional proportional-equation method to resolution of epinrphrine-norepine-phrine mixture at the 10-5mol·dm-3 level over the ratio range 1 ·6.88 - 2.91:1, with an error of less than ±5% and an average precision of about 2.5%.
出处
《化学学报》
SCIE
CAS
CSCD
北大核心
1995年第12期1198-1203,共6页
Acta Chimica Sinica
基金
国家自然科学基金资助的项目
