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两种采集SD大鼠脑脊液方法的比较 被引量:12

Two methods to collect cerebrospinal fluid in SD rats
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摘要 目的比较实验SD大鼠脑脊液采集的两种方法。方法SD大鼠分为2组,采用经侧脑室穿刺和经枕大孔穿刺法采集脑脊液,比较2种方法穿刺成功率。结果经枕大孔穿刺法成功率明显高于经侧脑室穿刺法。结论经枕大孔穿刺法进针直观、简便、损伤小,明显提高一次性穿刺成功率,并有效减少并发症的发生。 Objective To evaluate the two methods to collect cerebrospinal fluid in SD rats. Methods The cerebrpspinal fluid was collected through the lateral ventricle or the foramen magnum in rats. The rates of success of the two methods were compared. Results The foramen magnum method was found better than the lateral ventricle one. Conclusion The method of foramen magnum is more visual and convenient to operate, causing less injury and complications, and possesses high rate of success.
出处 《徐州医学院学报》 CAS 2005年第4期317-319,共3页 Acta Academiae Medicinae Xuzhou
关键词 SD大鼠 脑脊液 穿刺术 SD rats cerebrospinal fluid paracentesis
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参考文献2

  • 1Paxinos G, Watson C. The rat brain in Stereotaxic Coordinates [ M ].Second ed. Australia North Ryde: Academic Press, 1986.21.
  • 2Lai YL, Smith PM, Lamm WJ, et al. Sampling and analysis of cerebrospinal fluid for chronic studies in awake rats[ J]. J Appl Physiol, 1983,54(6): 1754 - 1757.

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