期刊文献+

肉毒碱治疗对维持性血透患者贫血的影响

在线阅读 下载PDF
导出
摘要 目的:观察静脉注射左旋卡尼汀(肉毒碱)对维持性血透患者贫血和临床症状、体征的影响。方法:对常规治疗一年以上的21例血透患者,在血透后静脉加注肉毒碱注射液2g,每周2次,为期1个月。采用自身前后对照方法,比较治疗前后血红蛋白、血球压积、白细胞计数、红细胞计数以及精神状态、食欲等7项临床症状及体征的变化。结果:21例维持性血透患者透前有16例患者血浆游离肉毒碱浓度低于正常,补充1个月后的血浆游离肉毒碱浓度和血红蛋白、红、白细胞计数明显上升。精神状态、食欲等7项临床指标也得到明显改善。结论:补充肉毒碱能改善维持性血透患者的临床表现和有助于增加促红细胞生成素的疗效,改善贫血。
出处 《温州医学院学报》 CAS 2005年第4期324-325,共2页 Journal of Wenzhou Medical College
  • 相关文献

参考文献2

二级参考文献9

  • 1[1]Borum PR. Plasma carnitine compartment and red blood cell carnitine compartment of healthy adults. Am J Clin Nutr, 1987,46:437-441
  • 2[2]Borum PR. Changing perspective of carnitine function and the need for exogenous carnitine of patients treated with hemodialysis. Am J Clin Nutr,1996,976-977
  • 3[3]Giovenali P, Fanocchio D, Montanari G, et al. Selective trophic effect of L-carnitine in type I and type II skeletal muscle fibers. Kidney Int,1994,46:1616-1619
  • 4[4]Gloggler A, Bulla M, Furst P. Effect of low dose supplementation of L-carnitine on lipid metabolism in hemodialysis children. Kidney Int,1989,36 (supple27): S256-S258
  • 5[5]Golper TA, Wolfson M,Ahmod S,et al. Multicenter trial of L-carnitine in maintenance hemodialysis patients. I.Carnitine concentrations and lipid effects. Kidney Int, 1990,38:904-911
  • 6[6]Kooistra MP, Sreugernberg A, Van ESA. The response to recombinant human erythropoietin in patients with the anemia of end-stage renal disease is correlated with serum carnitine levels. Nephron, 1991,57:127-128
  • 7[7]Boran M, Dalva I, Gonenc F,et al. Response to recombinant human erythropoietin(r-HuEPO) and L-carnitine combination in patients with anemia of end-stage renal disease. Nephron,1996,73:314-315
  • 8顾天爵.生物化学[M]人民卫生出版社,1993.
  • 9Asle Aarsland,Morten Lundquist,Bernt B?rretsen,Rolf K. Berge. On the effect of peroxisomal β-oxidation and carnitine palmitoyltransferase activity by eicosapentaenoic acid in liver and heart from rats[J] 1990,Lipids(9):546~548

共引文献30

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部