摘要
目的:分析和评估肺功能检测在小儿呼吸道疾病中的临床价值。方法:采用便携式肺功能仪检测6261例呼吸道疾病患儿。部分病例定期随访,对其中268例咳嗽变异性哮喘儿童(CVA),147例哮喘儿童(AS)治疗前后进行第1秒用力呼气容积(FEV1),用力肺活量(FVC),组变异率(PEFR)的自身对照,以及咳嗽变异性哮喘与哮喘儿童肺功能比较。结果:哮喘儿童经糖皮质激素气雾剂治疗后肺功能明显改善,治疗前FEV1(1.029±0.398)L,治疗后(1.180±0.427)L,治疗前FVC(1.147±0.468)L,治疗后(1.318±0.480)L,P<0.001。咳嗽变异性哮喘与哮喘儿童肺功能变化一致,咳嗽变异性哮喘组PEFR大于15%132例,小于15%136例,哮喘儿童组大于15%68例,小于15%79例,P>0.05。结论:肺功能检测是诊断哮喘必不可少的手段,为指导治疗,判断预后,评价疗效提供可靠的依据,应广泛推广于儿科临床。
Objective： To evaluate the clinical application of lung function analysis in diagnosis of children respiratory diseases. Methods： Respiratory function was evaluated with portable lung function detector in 6 261 children with respiratory diseases. FEV1 ,FVC and PEFR were measured in 268 children with cough variant asthma （CVA） and 147 children with asthma （AS）,and the results were self-compared during follow-up. Results： There were no significant differences in above parameters between children with cough variant asthma and those with asthma （P〉0. 05）. Lung functions of asthma children were improved evidently by administration of glycocorticoid inhalator （P〈0. 001）. Conclusion： Lung function detection is essential for diagnosis of asthma and it can be used as a reliable index for therapeutic effect of asthma children.
出处
《浙江大学学报（医学版）》
CAS
CSCD
2005年第4期365-367,共3页
Journal of Zhejiang University(Medical Sciences)
关键词
呼吸道疾病
哮喘/药物疗法
呼吸功能试验
咳嗽变异性哮喘
肺功能
Respiratory tract diseases
Asthma/drug ther
Respiratory function tests
Cough variant asthma
Lung function
