摘要
目的探讨单纯性肥胖儿童糖代谢、脂代谢情况、血压水平及胰岛素抵抗程度。方法采用随机对照的病例研究方法,分析年龄6～13岁单纯性肥胖儿童(n=53)与非肥胖同年龄组儿童(n=40),二者空腹血糖(FPG)、胰岛素抵抗指数(IRI)、甘油三酯(TG)、总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、动脉收缩压及舒张压水平的差异。结果肥胖组儿童FPG、IRI、TG、TC、LDL-C、收缩压水平均明显高于对照组(P<0.05),HDL-C水平则低于对照组(P<0.05)。肥胖组中存在高血压者8例(15.1%),脂代谢紊乱者19例(35.8%),FPG异常者3例(5.7%);同时存在高血压、脂代谢紊乱及FPG异常中2种及(或)以上异常者10例(18.9%)。结论单纯性肥胖儿童多存在不同程度的糖、脂代谢异常及血压异常,同时存在代谢综合征成份簇集的倾向。
[Objective] To investigate the prevalence of metabolism syndrome （MS） in primary obese children. [Methods] A randomized and controlled study was designed to analyzed the difference of fasting plasma glucose （FPG）, insulin resistance index（IRI）, serum triglyceride （TG）, total cholesterol （TC）, high density hpoprotein cholesterol （HDL-C）, low density lipoprotein cholesterol （LDL-C）, systolic blood pressure （SBP） and diastolic blood pressure between primary obese children group （n =53, aged from 6 to 13 years old） and control group （n =40）. [Results] Levels of FPG, IRI, TG, TC, LDL-C and SBP were significantly higher and HDL-C level was significantly lower in obesity group in obesity group than in control group （P 〈0.05）. Eight patients （15.1%） were found hypertension, 19（35.8%） were found dyslipoproteinemia and 3（5.7%） were found impaired fasting glucose in obesity group. Ten patients （18.9%） were found 2 or （and） more risk factors among hypertension, dyslipoproteinemia and impaired fasting glucose. [Conclusions] Some of primary obese children were suffered dysfunction of glycemia, blood lipid and blood pressure regulation, and even some were found been metabolism syndrome.
出处
《中国现代医学杂志》
CAS
CSCD
北大核心
2005年第15期2329-2331,共3页
China Journal of Modern Medicine
关键词
儿童
肥胖症
代谢综合征
children
obesity
metabolism syndrome
