摘要
测定肺结节病患者支气管肺泡灌洗液中血管紧张素转化酶（ＢＡＬＦ－ＡＣＥ）的水平。结果显示，活动性结节病的ＢＡＬＦ－ＡＣＥ水平明显高于对照组（Ｐ＜０．０５）。相关性分析表明，ＢＡＬＦ－ＡＣＥ与支气管肺泡灌洗液中淋巴细胞百分率有明显正相关（γ＝０．８７２３，Ｐ＜０．０１）。提示ＢＡＬＦ－ＡＣＥ在肺结节病的病理机制中起着重要作用，并可作为诊断肺结节病的一项敏感的生物学指标。
Determination of ACE was done in BALF in ll patients with sarcoidosis (study group)and 21 pateints with IPF or tuberculoma (control group).The results showed that BALF-ACE in sarcoidosis were significantly higher than that in control group (P<0.05).Correlation was gound between BALF-ACE and lymphocyte percentage (r=0.8723,P<0.01).It was suggested that BALF-ACE may play an important role in the pathogenesis of sarcoidosis,and can be taken as a sensitive biological indicator in the diagnosis and disease activity assessment of sarcoidosis.
出处
《南京医科大学学报（自然科学版）》
CAS
CSCD
1995年第3期561-563,共3页
Journal of Nanjing Medical University(Natural Sciences)
关键词
肺结节病
支气管肺泡
灌洗液
BALF-ACF
lung sarcoidosis, bronchoalveolar lavage fruid, angiotensin converting enzyme
